degenerated pancreas beta cells.ıs it possible replace them via stem cells.recent studies show that adult stem cells can not replace them but embryonic stem cells or adult beta cells replication is thought can replace.on the other hand dediferantation of cells for example pancreatic exocrine cells to pancreatic beta cells.ıt must be known which signaling mechamisms effects them to dedifferantie.ıt is releated with molecular biology.after dediferantation what must be done ı am interest with it deeper.maybe duplication of beta cells can be triggered in vivo but how it will be done.